Tatsächlich hat sich das Problem von selbst behoben. Gefällt mir zwar nicht, weil das nächste mal wenn der wieder nicht funktioniert nicht weis woran es lag aber aktuell läuft es. Stick ist ein ConBee 2 und dieser steckt im ersten USB Port des Raspberry Pi's 4 hab alternativ auch noch einen RaspBee2 der in die GPIO's gesteckt wird aber dieser funktionierte ebenso nicht welcher nun allerdings auch funktioniert...

Moin ich versuche seit ca 3 Tagen den Fehler zu finden und kann diesen leider nicht finden. Ich habe einen Conbee2 Stick von dresden Electronic. Ich habe in den Adaptereinstellungen schon alles mögliche probiert von dem langen COM Namen und den kurzen aber beides wirft mir leider den gleichen Fehler.
Anbei einmal der Log im Modus silly

host.iobroker
2021-11-21 11:39:58.666	info	Restart adapter system.adapter.zigbee.0 because enabled
host.iobroker
2021-11-21 11:39:58.665	error	instance system.adapter.zigbee.0 terminated with code 6 (UNCAUGHT_EXCEPTION)
host.iobroker
2021-11-21 11:39:58.665	error	Caught by controller[1]: at slip.Decoder.p.handleEnd (/opt/iobroker/node_modules/zigbee-herdsman/node_modules/slip/src/slip.js:189:18)
host.iobroker
2021-11-21 11:39:58.664	error	Caught by controller[1]: at Parser.onMessage (/opt/iobroker/node_modules/zigbee-herdsman/src/adapter/deconz/driver/parser.ts:30:14)
host.iobroker
2021-11-21 11:39:58.664	error	Caught by controller[1]: at Parser.emit (domain.js:475:12)
host.iobroker
2021-11-21 11:39:58.664	error	Caught by controller[1]: at Parser.emit (events.js:400:28)
host.iobroker
2021-11-21 11:39:58.663	error	Caught by controller[1]: at Driver.onParsed (/opt/iobroker/node_modules/zigbee-herdsman/src/adapter/deconz/driver/driver.ts:784:14)
host.iobroker
2021-11-21 11:39:58.663	error	Caught by controller[1]: at Driver.emit (domain.js:475:12)
host.iobroker
2021-11-21 11:39:58.663	error	Caught by controller[1]: at Driver.emit (events.js:400:28)
host.iobroker
2021-11-21 11:39:58.662	error	Caught by controller[1]: at Driver.<anonymous> (/opt/iobroker/node_modules/zigbee-herdsman/src/adapter/deconz/adapter/deconzAdapter.ts:63:59)
host.iobroker
2021-11-21 11:39:58.662	error	Caught by controller[1]: at processFrame (/opt/iobroker/node_modules/zigbee-herdsman/src/adapter/deconz/driver/frameParser.ts:405:59)
host.iobroker
2021-11-21 11:39:58.658	error	Caught by controller[1]: at parseFrame (/opt/iobroker/node_modules/zigbee-herdsman/src/adapter/deconz/driver/frameParser.ts:446:15)
host.iobroker
2021-11-21 11:39:58.658	error	Caught by controller[1]: Error: received frame size to small
host.iobroker
2021-11-21 11:39:58.657	error	Caught by controller[0]: This error originated either by throwing inside of an async function without a catch block, or by rejecting a promise which was not handled with .catch(). The promise rejected with the reason:

zigbee.0
2021-11-21 11:39:58.070	warn	Terminated (UNCAUGHT_EXCEPTION): Without reason

zigbee.0
2021-11-21 11:39:58.069	debug	Plugin sentry destroyed

zigbee.0
2021-11-21 11:39:58.066	info	terminating

zigbee.0
2021-11-21 11:39:57.567	info	Zigbee: disabling joining new devices.

zigbee.0
2021-11-21 11:39:57.564	info	cleaned everything up...

zigbee.0
2021-11-21 11:39:57.558	silly	States user redis pmessage zigbee.0.*/zigbee.0.info.connection:{"val":false,"ack":true,"ts":1637491197372,"q":0,"from":"system.adapter.zigbee.0","user":"system.user.admin","lc":1637486942725}

zigbee.0
2021-11-21 11:39:57.546	error	received frame size to small

zigbee.0
2021-11-21 11:39:57.545	error	Error: received frame size to small at parseFrame (/opt/iobroker/node_modules/zigbee-herdsman/src/adapter/deconz/driver/frameParser.ts:446:15) at processFrame (/opt/iobroker/node_modules/zigbee-herdsman/src/adapter/deconz/driver/frameParser.ts:405:59) at Driver.<anonymous> (/opt/iobroker/node_modules/zigbee-herdsman/src/adapter/deconz/adapter/deconzAdapter.ts:63:59) at Driver.emit (events.js:400:28) at Driver.emit (domain.js:475:12) at Driver.onParsed (/opt/iobroker/node_modules/zigbee-herdsman/src/adapter/deconz/driver/driver.ts:784:14) at Parser.emit (events.js:400:28) at Parser.emit (domain.js:475:12) at Parser.onMessage (/opt/iobroker/node_modules/zigbee-herdsman/src/adapter/deconz/driver/parser.ts:30:14) at slip.Decoder.p.handleEnd (/opt/iobroker/node_modules/zigbee-herdsman/node_modules/slip/src/slip.js:189:18)

zigbee.0
2021-11-21 11:39:57.383	error	unhandled promise rejection: received frame size to small

zigbee.0
2021-11-21 11:39:57.382	error	Unhandled promise rejection. This error originated either by throwing inside of an async function without a catch block, or by rejecting a promise which was not handled with .catch().

zigbee.0
2021-11-21 11:39:57.366	info	Installed Version: iobroker.zigbee@1.6.6

zigbee.0
2021-11-21 11:39:57.354	debug	Backup /opt/iobroker/iobroker-data/zigbee_0/backup_2021_11_21-11_39_56.tar.gz success

zigbee.0
2021-11-21 11:39:57.233	silly	States system redis pmessage system.adapter.zigbee.0.logLevel/system.adapter.zigbee.0.logLevel:{"val":"silly","ack":true,"ts":1637491197091,"q":0,"from":"system.adapter.zigbee.0","lc":1637491122058}

zigbee.0
2021-11-21 11:39:56.884	debug	Starting zigbee-herdsman...

zigbee.0
2021-11-21 11:39:56.883	info	Starting Zigbee npm ...

zigbee.0
2021-11-21 11:39:56.807	debug	Using zigbee-herdsman with settings: {"network":{"panID":6754,"channelList":[11],"networkKey":[1,3,5,7,9,11,13,15,0,2,4,6,8,10,12,13],"extenedPanID":[221,221,221,221,221,221,221,221]},"databasePath":"/opt/iobroker/iobroker-data/zigbee_0/shepherd.db","backupPath":"/opt/iobroker/iobroker-data/zigbee_0/nvbackup.json","serialPort":{"baudRate":115200,"rtscts":false,"path":"/dev/ttyACM0","adapter":"deconz"},"adapter":{"forceStartWithInconsistentAdapterConfiguration":false}}

zigbee.0
2021-11-21 11:39:56.749	info	starting. Version 1.6.6 in /opt/iobroker/node_modules/iobroker.zigbee, node: v14.18.1, js-controller: 3.3.19

zigbee.0
2021-11-21 11:39:56.491	debug	Plugin sentry Initialize Plugin (enabled=true)
host.iobroker
2021-11-21 11:39:53.630	info	instance system.adapter.zigbee.0 started with pid 14632
host.iobroker
2021-11-21 11:39:23.582	info	Restart adapter system.adapter.zigbee.0 because enabled
host.iobroker
2021-11-21 11:39:23.581	error	instance system.adapter.zigbee.0 terminated with code 6 (UNCAUGHT_EXCEPTION)
host.iobroker
2021-11-21 11:39:23.580	error	Caught by controller[1]: at /opt/iobroker/node_modules/zigbee-herdsman/node_modules/@serialport/stream/lib/index.js:242:12
host.iobroker
2021-11-21 11:39:23.579	error	Caught by controller[1]: at SerialPort._error (/opt/iobroker/node_modules/zigbee-herdsman/node_modules/@serialport/stream/lib/index.js:198:14)
host.iobroker
2021-11-21 11:39:23.578	error	Caught by controller[1]: at SerialPort.<anonymous> (/opt/iobroker/node_modules/zigbee-herdsman/src/adapter/deconz/driver/driver.ts:182:28)
host.iobroker
2021-11-21 11:39:23.578	error	Caught by controller[1]: Error: Error while opening serialport 'Error: Error Resource temporarily unavailable Cannot lock port'
host.iobroker
2021-11-21 11:39:23.576	error	Caught by controller[0]: This error originated either by throwing inside of an async function without a catch block, or by rejecting a promise which was not handled with .catch(). The promise rejected with the reason:

zigbee.0
2021-11-21 11:39:22.983	warn	Terminated (UNCAUGHT_EXCEPTION): Without reason

zigbee.0
2021-11-21 11:39:22.982	debug	Plugin sentry destroyed

zigbee.0
2021-11-21 11:39:22.979	info	terminating

zigbee.0
2021-11-21 11:39:22.481	info	Zigbee: disabling joining new devices.

zigbee.0
2021-11-21 11:39:22.477	info	cleaned everything up...

zigbee.0
2021-11-21 11:39:22.460	error	Error while opening serialport 'Error: Error Resource temporarily unavailable Cannot lock port'

zigbee.0
2021-11-21 11:39:22.459	error	Error: Error while opening serialport 'Error: Error Resource temporarily unavailable Cannot lock port' at SerialPort.<anonymous> (/opt/iobroker/node_modules/zigbee-herdsman/src/adapter/deconz/driver/driver.ts:182:28) at SerialPort._error (/opt/iobroker/node_modules/zigbee-herdsman/node_modules/@serialport/stream/lib/index.js:198:14) at /opt/iobroker/node_modules/zigbee-herdsman/node_modules/@serialport/stream/lib/index.js:242:12

zigbee.0
2021-11-21 11:39:22.456	error	unhandled promise rejection: Error while opening serialport 'Error: Error Resource temporarily unavailable Cannot lock port'

zigbee.0
2021-11-21 11:39:22.453	error	Unhandled promise rejection. This error originated either by throwing inside of an async function without a catch block, or by rejecting a promise which was not handled with .catch().

zigbee.0
2021-11-21 11:39:02.814	silly	States user redis pmessage zigbee.0.*/zigbee.0.info.connection:{"val":false,"ack":true,"ts":1637491142812,"q":0,"from":"system.adapter.zigbee.0","user":"system.user.admin","lc":1637486942725}

zigbee.0
2021-11-21 11:39:02.811	silly	States user redis pmessage zigbee.0.*/zigbee.0.info.pairingMessage:{"val":"Error: Starting zigbee-herdsman problem : \"Error while opening serialport 'Error: Error Resource temporarily unavailable Cannot lock port'\". undefined","ack":true,"ts":1637491142809,"q":0,"from":"system.adapter.zigbee.0","user":"system.user.admin","lc":1637491142809}

zigbee.0
2021-11-21 11:39:02.796	error	Error herdsman start

zigbee.0
2021-11-21 11:39:02.793	error	Failed to start Zigbee

zigbee.0
2021-11-21 11:39:02.792	error	Starting zigbee-herdsman problem : "Error while opening serialport 'Error: Error Resource temporarily unavailable Cannot lock port'"

zigbee.0
2021-11-21 11:39:02.441	info	Installed Version: iobroker.zigbee@1.6.6

zigbee.0
2021-11-21 11:39:02.392	debug	Starting zigbee-herdsman...

zigbee.0
2021-11-21 11:39:02.391	info	Starting Zigbee npm ...

zigbee.0
2021-11-21 11:39:02.389	info	Try to reconnect. 1 attempts left

zigbee.0
2021-11-21 11:38:52.526	silly	States user redis pmessage zigbee.0.*/zigbee.0.info.connection:{"val":false,"ack":true,"ts":1637491132520,"q":0,"from":"system.adapter.zigbee.0","user":"system.user.admin","lc":1637486942725}

zigbee.0
2021-11-21 11:38:52.520	silly	States user redis pmessage zigbee.0.*/zigbee.0.info.pairingMessage:{"val":"Error: Starting zigbee-herdsman problem : undefined. undefined","ack":true,"ts":1637491132517,"q":0,"from":"system.adapter.zigbee.0","user":"system.user.admin","lc":1637491132517}

zigbee.0
2021-11-21 11:38:52.384	error	Error herdsman start

zigbee.0
2021-11-21 11:38:52.383	error	Failed to start Zigbee

zigbee.0
2021-11-21 11:38:52.382	error	Starting zigbee-herdsman problem : undefined

zigbee.0
2021-11-21 11:38:42.365	silly	States user redis pmessage zigbee.0.*/zigbee.0.info.connection:{"val":false,"ack":true,"ts":1637491122358,"q":0,"from":"system.adapter.zigbee.0","user":"system.user.admin","lc":1637486942725}

zigbee.0
2021-11-21 11:38:42.353	info	Installed Version: iobroker.zigbee@1.6.6

zigbee.0
2021-11-21 11:38:42.341	debug	Backup /opt/iobroker/iobroker-data/zigbee_0/backup_2021_11_21-11_38_41.tar.gz success

zigbee.0
2021-11-21 11:38:42.215	silly	States system redis pmessage system.adapter.zigbee.0.logLevel/system.adapter.zigbee.0.logLevel:{"val":"silly","ack":true,"ts":1637491122058,"q":0,"from":"system.adapter.zigbee.0","lc":1637491122058}

zigbee.0
2021-11-21 11:38:41.851	debug	Starting zigbee-herdsman...

zigbee.0
2021-11-21 11:38:41.850	info	Starting Zigbee npm ...

zigbee.0
2021-11-21 11:38:41.789	debug	Using zigbee-herdsman with settings: {"network":{"panID":6754,"channelList":[11],"networkKey":[1,3,5,7,9,11,13,15,0,2,4,6,8,10,12,13],"extenedPanID":[221,221,221,221,221,221,221,221]},"databasePath":"/opt/iobroker/iobroker-data/zigbee_0/shepherd.db","backupPath":"/opt/iobroker/iobroker-data/zigbee_0/nvbackup.json","serialPort":{"baudRate":115200,"rtscts":false,"path":"/dev/ttyACM0","adapter":"deconz"},"adapter":{"forceStartWithInconsistentAdapterConfiguration":false}}

zigbee.0
2021-11-21 11:38:41.737	info	starting. Version 1.6.6 in /opt/iobroker/node_modules/iobroker.zigbee, node: v14.18.1, js-controller: 3.3.19

zigbee.0
2021-11-21 11:38:41.461	debug	Plugin sentry Initialize Plugin (enabled=true)

zigbee.0
2021-11-21 11:38:41.254	debug	statesDB connected

zigbee.0
2021-11-21 11:38:41.253	debug	States connected to redis: 127.0.0.1:9000

zigbee.0
2021-11-21 11:38:41.245	debug	States create User PubSub Client

zigbee.0
2021-11-21 11:38:41.243	debug	States create System PubSub Client

zigbee.0
2021-11-21 11:38:41.236	debug	Redis States: Use Redis connection: 127.0.0.1:9000

zigbee.0
2021-11-21 11:38:41.233	debug	objectDB connected

zigbee.0
2021-11-21 11:38:41.226	silly	redis psubscribe cfg.o.system.user.*

zigbee.0
2021-11-21 11:38:41.223	debug	Objects connected to redis: 127.0.0.1:9001

zigbee.0
2021-11-21 11:38:41.210	debug	Objects client initialize lua scripts

zigbee.0
2021-11-21 11:38:41.209	debug	Objects create User PubSub Client

zigbee.0
2021-11-21 11:38:41.207	debug	Objects create System PubSub Client

zigbee.0
2021-11-21 11:38:41.205	debug	Objects client ready ... initialize now

zigbee.0
2021-11-21 11:38:41.167	debug	Redis Objects: Use Redis connection: 127.0.0.1:9001

Es wäre grandios wenn jemand das gleiche Problem + Lösung hat